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Todays presentation is structured into four main sections. First, well discuss our core technical innovations including biology-aware chunking, geometric embeddings, and cross-enzyme attention mechanisms. Second, well examine the system architecture and performance through ablation studies and embedding space validation. Third, well present empirical validation through drug-drug interaction prediction and substrate specificity case studies. Finally, well cover the implementation details, comparative analysis with baseline methods, and the research challenges we overcame. Throughout this presentation, youll see how we integrate 3D structural analysis of Cytochrome P450 enzymes with retrieval-augmented generation to achieve unprecedented accuracy in drug metabolism prediction. |
IEEE/ICACT20260263 Slide.02
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